ARTN Protéine
Aperçu rapide pour ARTN Protéine (ABIN935222)
Antigène
Voir toutes ARTN ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG
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Attributs du produit
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Purified recombinant Human Artemin protein
Expression System: E.coli
Bioactivity: Determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons. -
Purification
- Heat shock method
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niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Artemin (ARTN) (AA 112-224) protein (Fc Tag)
ARTN Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Artemin (ARTN) (AA 108-220) protein (His-IF2DI Tag)ARTN Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Artemin (ARTN) (AA 108-220) protein (Fc Tag)ARTN Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Artemin (ARTN) (AA 1-228) protein (GST tag)ARTN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Artemin (ARTN) proteinARTN Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 98,00% SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- ARTN (Artemin (ARTN))
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Autre désignation
- Artemin
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Sujet
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Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons.
Alternative Names: EVN protein, Enovin protein, ART protein, Neublastin protein , ARTN protein, NBN protein -
Poids moléculaire
- 24.4 kDa
Antigène
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