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GDF6 Protéine

Protéine Recombinant GDF6 exprimée dans Escherichia coli (E. coli).
N° du produit ABIN935239

Aperçu rapide pour GDF6 Protéine (ABIN935239)

Antigène

Voir toutes GDF6 Protéines
GDF6 (Growth Differentiation Factor 6 (GDF6))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 4
  • 2
  • 1
  • 1
Humain

Source

  • 6
  • 2
Escherichia coli (E. coli)

Pureté

> 95 % pure
  • Séquence

    TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

    Attributs du produit

    Purified recombinant Human BMP13 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/mL.

    niveau d'endotoxine

    < 0.1 ng per μg (1 EU/μg).
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  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Commentaires

    Biological activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 μg/mL.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

    Buffer

    Supplied lyophilized with no additives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Antigène

    GDF6 (Growth Differentiation Factor 6 (GDF6))

    Autre désignation

    BMP13

    Sujet

    BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
    Alternative Names: BMP-13 protein, BMP-13, BMP 13, CDMP-2 protein, BMP-13 protein, Cartilage-Derived Morphogenetic Protein-2 protein, Bone Morphogenetic protein 13 protein, BMP13, GDF-6 protein, BMP 13 protein

    Poids moléculaire

    27.5 kDa
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