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FGF acidic (Active) Protéine

Cette protéine Recombinant est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN935373

Aperçu rapide pour FGF acidic (Active) Protéine (ABIN935373)

Antigène

FGF acidic

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 2
  • 1
  • 1
Humain

Source

  • 4
Escherichia coli (E. coli)

Pureté

> 95 % pure
  • Séquence

    MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

    Attributs du produit

    Purified recombinant Human FGF acidic protein
    Expression System: E.coli
    Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ? 0.5 ng/mL corresponding to a specific activity of ? 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ? 0.2 ng/mL in the presence of 10 µg/mL heparin, corresponding to a specific activity of ? 5 x 10^6 units/mg.

    niveau d'endotoxine

    < 0.1 ng per µg (1 EU/µg).
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  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    RT/-20 °C
  • Antigène

    FGF acidic

    Sujet

    FGF acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF acidic has the ability to signal through all the FGF receptors.
    Alternative Names: FGF-1 protein, ECGF-beta protein, HBGF-1 protein, Fibroblast Growth Factor-acidic protein

    Poids moléculaire

    15.9 kDa
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