IL-17 Protéine
IL17
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Antigène Voir toutes IL-17 (IL17) Protéines
- IL-17 (IL17) (Interleukin 17 (IL17))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
- Attributs du produit
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Purified recombinant Human IL17 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/mL. Assay #2: Measured by its ability to induce IL-6 production by NHDF cells. - Pureté
- > 98 % pure
- niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL17 Protéine
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
- Buffer
- Supplied lyophilized with no additives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- RT/-20 °C
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- Antigène
- IL-17 (IL17) (Interleukin 17 (IL17))
- Autre désignation
- IL17 (IL17 Produits)
- Synonymes
- CTLA8 Protein, IL-17 Protein, IL-17A Protein, IL17 Protein, Ctla-8 Protein, Ctla8 Protein, Il17 Protein, ChIL-17 Protein, IL-17F Protein, IL17A Protein, CTLA-8 Protein, interleukin 17A Protein, IL17A Protein, Il17a Protein
- Sujet
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The originally described IL17 protein, now known as IL17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.
Alternative Names: IL-17, Interleukin 17 protein, IL-17 protein, IL17, IL 17, CTLA-8 protein, IL-17 protein, IL 17 protein - Poids moléculaire
- 31 kDa
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