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IL-31 Protéine

IL31 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 98 % pure Active
N° du produit ABIN935492
  • Antigène Voir toutes IL-31 (IL31) Protéines
    IL-31 (IL31) (Interleukin 31 (IL31))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 12
    • 5
    • 4
    • 2
    • 1
    Humain
    Source
    • 12
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Séquence
    SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
    Attributs du produit
    Purified recombinant Human IL31 protein
    Expression System: E.coli
    Bioactivity: Measured by its ability to induce STAT3 activation in human U87 cells.
    Pureté
    > 98 % pure
    niveau d'endotoxine
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL31 Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with distilled water to a concentration of 0.1 - 0.5 mg/mL.
    Buffer
    Lyophilized from 10 mM Na3PO4, pH 7.5.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    RT/-20 °C
  • Antigène
    IL-31 (IL31) (Interleukin 31 (IL31))
    Autre désignation
    IL31 (IL31 Produits)
    Synonymes
    IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
    Sujet
    Human IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
    Alternative Names: Interleukin 31 protein, IL 31, IL 31 protein, IL31, IL-31, IL-31 protein, IL-31 protein
    Poids moléculaire
    15.8 kDa
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