IL-31 Protéine
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- Antigène Voir toutes IL-31 (IL31) Protéines
- IL-31 (IL31) (Interleukin 31 (IL31))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
- Attributs du produit
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Purified recombinant Human IL31 protein
Expression System: E.coli
Bioactivity: Measured by its ability to induce STAT3 activation in human U87 cells. - Pureté
- > 98 % pure
- niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL31 Protéine
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with distilled water to a concentration of 0.1 - 0.5 mg/mL.
- Buffer
- Lyophilized from 10 mM Na3PO4, pH 7.5.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- RT/-20 °C
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- Antigène
- IL-31 (IL31) (Interleukin 31 (IL31))
- Autre désignation
- IL31 (IL31 Produits)
- Synonymes
- IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
- Sujet
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Human IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
Alternative Names: Interleukin 31 protein, IL 31, IL 31 protein, IL31, IL-31, IL-31 protein, IL-31 protein - Poids moléculaire
- 15.8 kDa
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