ILGFBP1 (full length) (Active) Protéine
Aperçu rapide pour ILGFBP1 (full length) (Active) Protéine (ABIN935502)
Antigène
Type de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- full length
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Attributs du produit
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Purified recombinant Human ILGFBP1 protein
Expression System: E.coli
Bioactivity: Inhibition of IGF-I stimulated proliferation of NUC-1 cells: IC50 ~ 100 ng/mL Inhibition of serum-induced stimulation of DNA synthesis in chick embryo fibroblast primary cultures: IC50 (1 % serum) ~300 ng/mL.
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 20 mM CH3COOH at the stock concentration of not less than 0.1 mg/mL.
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- ILGFBP1
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Sujet
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IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative Names: ILGFBP-1, hIGFBP-1 protein, PP12 protein, ILGFBP1, ILGFBP 1, ILGFBP-1 protein, ILGFBP-1 protein, AFBP protein, ILGFBP 1 protein, IGF-BP25 protein, IGF-Binding Protein 1 protein, IBP-1 protein, IGFBP-1 protein, Insulin Like Growth Factor Binding Protein 1 protein -
Poids moléculaire
- 25.3 kDa
Antigène
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