Cardiotrophin 2 Protein (CTF2)
Aperçu rapide pour Cardiotrophin 2 Protein (CTF2) (ABIN935693)
Antigène
Voir toutes Cardiotrophin 2 (CTF2) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MAPISPSEPI GQAYSLALYM QKNTSALLQT YLQHQGSPFS DPGFSAPELQ LSTLPSAAVS FKTWHAMEDA ERLSRAQGAF LALTQHLQLV GDDQSYLNPG SPILLAQLGA ARLRAQGLLG NMAAIMTALG LPIPPEEDTL GFVPFGASAF ERKCRGYIVT REYGHWTDRA VRDLALLKAK YSA
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Attributs du produit
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Purified recombinant Mouse Neuropoietin protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 0.5-0.8 µg/mL. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Cardiotrophin 2 (CTF2)
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Autre désignation
- Neuropoietin
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Sujet
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Neuropoietin is a newly identified member of the IL6 cytokine family. Members of this family, including IL6, IL11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-a component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF2.
Alternative Names: NPO protein, NP protein -
Poids moléculaire
- 19.8 kDa
Antigène
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