SERPINB2 Protéine
Aperçu rapide pour SERPINB2 Protéine (ABIN935740)
Antigène
Voir toutes SERPINB2 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVT PMTPENFTSC GFMQQIQKGS YPDAILQAQA ADKIHSSFRS LSSAINASTG N YLLESVNK LFGEKSASFR EEYIRLCQKY YSSEPQAVDF LECAEEARKK INSWVKTQTK GK IPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REK LNIGYI EDLKAQILEL PYAGDVSMFL LLPDEIADVS TGLELLESEI TYDKLNKWTS KDKM AEDEV EVYIPQFKLE EHYELRSILR SMGMEDAFNK GRANFSGMSE RNDLFLSEVF HQAMV DVNE EGTEAAAGTG GVMTGRTGHG GPQFVADHPF LFLIMHKITN CILFFGRFSS P
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Attributs du produit
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Purified recombinant Human PAI2 protein
Expression System: E.coli
Bioactivity: Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 370C. Half maximal inhibition against 1.0 µg/mL of single chain tPA was obtained at a concentration of 1.0 µg/mL -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 13.711,36 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 15.754,29 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (His tag)
custom-made SERPINB2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (His tag)custom-made SERPINB2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (GST tag)SERPINB2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 50 MM CH3COONa, with 100 mM NaCl.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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Autre désignation
- PAI2
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Classe de substances
- Amino Acid
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Sujet
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PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47 kDa nonglycosylated intracellular protein which can be induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions.
Alternative Names: Plasminogen Activator Inhibitor-2 protein, Urokinase Inhibitor protein, PAI 2, PAI-2 protein, PAI2, PAI-2 protein, PAI 2 protein, PAI-2 -
Pathways
- Autophagy
Antigène
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