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SLIT2 Protéine

SLIT2 Origine: Humain Hôte: HEK-293T Cells Recombinant > 98 % pure
N° du produit ABIN935807
  • Antigène Voir toutes SLIT2 Protéines
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    Type de proteíne
    Recombinant
    Origine
    • 11
    • 5
    • 3
    Humain
    Source
    • 7
    • 6
    • 4
    • 1
    • 1
    HEK-293T Cells
    Séquence
    QACPAQCSCS GSTVDCHGLA LRSVPRNIPR NTERLDLNGN NITRITKTDF AGLRHLRVLQ LMENKISTIE RGAFQDLKEL ERLRLNRNHL QLFPELLFLG TAKLYRLDLS ENQIQAIPRK AFRGAVDIKN LQLDYNQISC IEDGAFRALR DLEVLTLNNN NITRLSVASF NHMPKLRTFR LHSNNLYCDC HLAWLSDWLR QRPRVGLYTQ CMGPSHLRGH NVAEVQKREF VCSGHQSFMA PSCSVLHCPA ACTCSNNIVD CRGKGLTEIP TNLPETITEI RLEQNTIKVI PPGAFSPYKK LRRIDLSNNQ ISELAPDAFQ GLRSLNSLVL YGNKITELPK SLFEGLFSLQ LLLLNANKIN CLRVDAFQDL HNLNLLSLYD NKLQTIAKGT FSPLRAIQTM HLAQNPFICD CHLKWLADYL HTNPIETSGA RCTSPRRLAN KRIGQIKSKK FRCSAKEQYF IPGTEDYRSK LSGDCFADLA CPEKCRCEGT TVDCSNQKLN KIPEHIPQYT AELRLNNNEF TVLEATGIFK KLPQLRKINF SNNKITDIEE GAFEGASGVN EILLTSNRLE NVQHKMFKGL ESLKTLMLRS NRITCVGNDS FIGLSSVRLL SLYDNQITTV APGAFDTLHS LSTLNLLANP FNCNCYLAWL GEWLRKKRIV TGNPRCQKPY FLKEIPIQDV AIQDFTCDDG NDDNSCSPLS RCPTECTCLD TVVRCSNKGL KVLPKGIPRD VTELYLDGNQ FTLVPKELSN YKHLTLIDLS NNRISTLSNQ SFSNMTQLLT LILSYNRLRC IPPRTFDGLK SLRLLSLHGN DISVVPEGAF NDLSALSHLA IGANPLYCDC NMQWLSDWVK SEYKEPGIAR CAGPGEMADK LLLTTPSKKF TCQGPVDVNI LAKCNPCLSN PCKNDGTCNS DPVDFYRCTC PYGFKGQDCD VPIHACISNP CKHGGTCHLK EGEEDGFWCI CADGFEGENC EVNVDDCEDN DCENNSTCVD GINNYTCLCP PEYTGELCEE KLDFCAQDLN PCQHDSKCIL TPKGFKCDCT PGYVGEHCDI DFDDCQDNKC KNGAHCTDAV NGYTCICPEG YSGLFCEFSP PMV
    Attributs du produit
    Purified recombinant Human SLIT2 N protein
    Expression System: 293 cells
    Pureté
    > 98 % pure
    niveau d'endotoxine
    < 0.1 ng per µg (1 EU/µg)
    Top Product
    Discover our top product SLIT2 Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in distilled water for a concentration of 0.1 to 1.0 g/mL. Do not vortex.
    Buffer
    Lyophilized from 20 mM Tris and 200 mM Arginine, pH 8.8.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Antigène
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    Autre désignation
    SLIT2N (SLIT2 Produits)
    Synonymes
    SLIL3 Protein, Slit-2 Protein, Drad-1 Protein, E030015M03Rik Protein, E130320P19Rik Protein, Slil3 Protein, mKIAA4141 Protein, Slit Protein, slil3 Protein, slit-2 Protein, slit2-a Protein, SLIT2 Protein, slit guidance ligand 2 Protein, slit homolog 2 (Drosophila) Protein, slit guidance ligand 2 S homeolog Protein, SLIT2 Protein, Slit2 Protein, slit2 Protein, slit2.S Protein
    Sujet
    Slit2 is a member of the Slit family that signals through the Roundabout (Robo) receptor as a repellent for axon guidance and neuronal migration, and can also act as a chemoattractant to vascular endothelial cells and a chemotaxis inhibitor for leukocytes. Slit2 is expressed primarily in the fetal lung, kidney, and adult spinal cord, and to a lesser extent in adult adrenal gland, thyroid and trachea. Slit2 is initially synthesized as a 1499 amino acid precursor, which is subsequently cleaved into N-terminal and C-terminal fragments, designated as Slit2-N and Slit2-C respectively. The neurodevelopment related activities, as measured by the ability to repel olfactory bulb axons and to induce branching in dorsal root ganglia axons, are contained only in the N-terminal fragment.
    Alternative Names: SLIL3 protein, Slit homolog 2 protein protein, Slit-2 N protein
    Poids moléculaire
    120-140 kDa
    Pathways
    Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
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