COL18A1 Protéine
Aperçu rapide pour COL18A1 Protéine (ABIN987805)
Antigène
Voir toutes COL18A1 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du produit
- Determined by Endothelial Cell Tube Formation. The cells treated with 10myg/ml Endostatin showed significant anti-angiogenesis effect.
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niveau d'endotoxine
- level is less than 0.1 ng per myg (1EU/myg) of Endostatin
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Stock
- -20 °C
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- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
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Autre désignation
- Endostatin
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Classe de substances
- Chemical
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Sujet
- Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues. Synonym: Endostatin 3 3 . Formulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. .
Antigène
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