IL-33 Protéine
Aperçu rapide pour IL-33 Protéine (ABIN988078)
Antigène
Voir toutes IL-33 (IL33) ProtéinesActivité biologique
Origine
Source
Pureté
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Séquence
- SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSK
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Attributs du produit
- Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106units/mg.
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niveau d'endotoxine
- Level Less than 1EU/µg of rMuIL-33 as determined by LAL method
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
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Stock
- 4 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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Autre désignation
- Interleukin-33 (IL-33)
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Sujet
- IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Mouse. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, EDTA and DTT, pH 7.4.
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Poids moléculaire
- Approximately 17.5 kDa protein containing 158 amino acid residues.
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Pathways
- Production of Molecular Mediator of Immune Response
Antigène
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