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PTAFR Protéines

(Platelet-Activating Factor Receptor (PTAFR))

This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].

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PTAFR Protein (AA 1-342) (His tag)

custom-made PTAFR Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PTAFR Protein, UniprotID P25105

3 images

N° du produit ABIN7551095

Détails

PTAFR Protein (AA 1-341) (His tag)

custom-made PTAFR Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ptafr Protein, UniprotID Q62035

3 images

N° du produit ABIN7557753

Détails

PTAFR Protein (His tag)

PTAFR Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

N° du produit ABIN7415482

Détails

PTAFR Protéine

PTAFR Origine: Humain Hôte: Wheat germ Recombinant AP

N° du produit ABIN1330436

Détails

PTAFR Protein (DYKDDDDK Tag,Strep Tag)

PTAFR Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc Imm, ELISA, cryo-EM, PhD, SPR

N° du produit ABIN7596925

Détails

PTAFR Protéine

PTAFR Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc

N° du produit ABIN7538480

Détails

PTAFR Protein (AA 1-341) (Strep Tag)

custom-made PTAFR Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3123109

Détails

PTAFR Protein (AA 1-342) (Strep Tag)

custom-made PTAFR Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3113246