PTGER4 Produits
(Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
Catégories
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008].
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Catégories PTGER4 en vedette
PTGER4 Anticorps
High quality antibodies with extensive validation data.
PTGER4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTGER4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey
Application
IHC (p), IHC, ICC
Validations
- (5)
N° du produit
ABIN1049257
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Rat
Application
IHC (p), IHC, ICC
Validations
- (5)
N° du produit
ABIN1049258
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (3)
N° du produit
ABIN6259076
Quantité
100 μL
Fiche technique
Fiche technique
PTGER4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316732
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316734
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3085887
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTGER4
: "Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice." dans: JCI insight, Vol. 3, Issue 3, (2018) (PubMed).: "Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis." dans: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling." dans: Cell death & disease, Vol. 7, pp. e2154, (2016) (PubMed).
: "Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells." dans: Endocrinology, Vol. 157, Issue 2, pp. 692-704, (2016) (PubMed).
: "The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii)." dans: Prostaglandins & other lipid mediators, Vol. 124, pp. 9-15, (2016) (PubMed).
: "Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model." dans: Cancer biology & therapy, Vol. 16, Issue 6, pp. 922-32, (2015) (PubMed).
: "Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF-κB pathways as well as Cox-2-mediated PGE2 /EP receptor signalling to enhance clathrin-mediated virus ..." dans: Cellular microbiology, Vol. 17, Issue 7, pp. 967-87, (2015) (PubMed).
: "Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 154, (2015) (PubMed).
: "Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-κB." dans: European journal of pharmacology, Vol. 742, pp. 81-8, (2014) (PubMed).
: "Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties." dans: Breast cancer research and treatment, Vol. 143, Issue 1, pp. 19-31, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à PTGER4
prostaglandin E receptor 4 (PTGER4), prostaglandin E receptor 4 (subtype EP4) (PTGER4), prostaglandin E receptor 4 (subtype EP4) a (ptger4a), prostaglandin E receptor 4 (ptger4), prostaglandin E receptor 4 subtype EP4 (ptger4), prostaglandin E receptor 4 (subtype EP4) (Ptger4), prostaglandin E receptor 4 (Ptger4), EP4, ep4, EP4R, PGE2R-EP4, Ptger, ptger4, PTGER4, ptger4l, Ptgerep4Protein level used designations for PTGER4
- prostaglandin E receptor 4, subtype EP4
- prostaglandin E2 receptor EP4 subtype
- prostaglandin E2 receptor subtype 4
- prostaglandin E receptor 4 (subtype EP4)
- ep4
- ep4a
- prostaglandin E receptor 4
- prostaglandin E receptor 4 subtype EP4
- PGE receptor EP4 subtype
- PGE receptor, EP4 subtype
- PGE2 receptor EP4 subtype
- prostanoid EP4 receptor
- prostaglandin E receptor 4 (EP4 subtype)
- prostaglandin E receptor EP4 subtype
- prostaglandin E2 receptor type 4
- PGE receptor, subtype EP4
- prostaglandin receptor EP4 subtype
- prostaglandin E2 subtype EP4 receptor
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