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Rabphilin anticorps (pSer234)

L’anticorps Lapin Polyclonal anti-Rabphilin a été validé pour IHC et WB. Il convient pour détecter Rabphilin dans des échantillons de Souris et Rat.
N° du produit ABIN5688892

Aperçu rapide pour Rabphilin anticorps (pSer234) (ABIN5688892)

Antigène

Rabphilin (RPH)

Reactivité

Souris, Rat

Hôte

Lapin

Clonalité

Polyclonal

Application

Immunohistochemistry (IHC), Western Blotting (WB)
  • Épitope

    pSer234

    Purification

    Affinity Purified

    Immunogène

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser234 of rabphilin 3A.
  • Indications d'application

    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    Stock

    -20 °C

    Stockage commentaire

    Rabphilin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Antigène

    Rabphilin (RPH)

    Autre désignation

    Rabphilin

    Sujet

    Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).

    Poids moléculaire

    82 kDa

    ID gène

    171039

    UniProt

    P47709
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