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Rabphilin anticorps (pSer234)

RPH Reactivité: Souris, Rat IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5688892
  • Antigène
    Rabphilin (RPH)
    Épitope
    pSer234
    Reactivité
    Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Affinity Purified
    Immunogène
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser234 of rabphilin 3A.
  • Indications d'application
    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Rabphilin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Antigène
    Rabphilin (RPH)
    Autre désignation
    Rabphilin
    Sujet
    Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).
    Poids moléculaire
    82 kDa
    ID gène
    171039
    UniProt
    P47709
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