Raet1d anticorps (PE)
Cet anticorps anti-Raet1d est un anticorps Souris Monoclonal détectant Raet1d dans FACS. Adapté pour Souris.
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N° du produit ABIN2663873
Aperçu rapide pour Raet1d anticorps (PE) (ABIN2663873)
Antigène
Raet1d
(Retinoic Acid Early Transcript delta (Raet1d))
Reactivité
Souris
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp Raet1d est conjugé à/à la PE
Application
Flow Cytometry (FACS)
Clone
Charlotte d1-23
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Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Raet1d (Retinoic Acid Early Transcript delta (Raet1d))
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Autre désignation
- RAE-1delta
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Sujet
- RAE-1δ is one of the five RAE-1 family, GPI-linked membrane protein consisting of alpha, beta, gamma, delta, and epsilon. They are strong homology within the family, related by 92 % -95 % sequence identity. They are distantly related to MHC class I proteins. RAE-1 proteins are abundantly expressed in fetal tissues, but not in normal adult tissue. They are constitutively expressed on some tumors and can be induced by retinoid acid. Its ligand NKG2D is found on NK cells, many transformed cell lines, and LPS-stimulated peritoneal macrophages. The interaction of NKG2D with RAE-1 transmits stimulatory signals to NK cells and other hematopoietic cells, leading to enhanced proliferation, cytokine secretion and target killing. They are involved in the regulation of innate and immune cytotoxic responses to tumors, pathogen-infected cells, and autoimmune diseases.
Antigène
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