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RRP8 Protéines

(Ribosomal RNA Processing 8 (RRP8))

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

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RRP8 Protein (AA 1-457) (His tag)

custom-made RRP8 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Rrp8 Protein, UniprotID Q9DB85

3 images

N° du produit ABIN7565004

Détails

RRP8 Protein (AA 1-456) (His tag)

custom-made RRP8 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant RRP8 Protein, UniprotID O43159

3 images

N° du produit ABIN7555285

Détails

RRP8 Protein (AA 1-456) (GST tag)

RRP8 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Ribosomal RNA Processing 8 (RRP8) (AA 1-456) protein (GST tag) (ABIN1308572)

1 image

N° du produit ABIN1308572

Détails

RRP8 Protein (AA 1-457) (Strep Tag)

custom-made RRP8 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3137122

Détails

RRP8 Protein (AA 1-456) (Strep Tag)

custom-made RRP8 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3095127