The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008].
Kim, Denli, Wright, Baul, Clemenson, Morcos, Zhao, Schafer, Gage, Kagalwala: "REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 44, pp. 14872-84, (2015) (PubMed).
Pseudonymes pour SCG2 Protéines
secretogranin II L homeolog (scg2.L) Protéines secretogranin II (chromogranin C), b (scg2b) Protéines secretogranin II (scg2) Protéines secretogranin II (SCG2) Protéines Secretogranin-2 (scg2) Protéines secretogranin II (Scg2) Protéines Chcg Protéines CHGC Protéines Chgc Protéines DKFZp459O193 Protéines EM66 Protéines LOC397939 Protéines MGC84703 Protéines MGC145924 Protéines scg2 Protéines SCG2 Protéines SCGG2 Protéines SgII Protéines SN Protéines wu:fj34e01 Protéines zgc:153925 Protéines