SEMA4D/CD100 Produits
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Catégories
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system\; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).
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Catégories SEMA4D/CD100 en vedette
SEMA4D/CD100 Anticorps
High quality antibodies with extensive validation data.
SEMA4D/CD100 Kits ELISA
Reliable ELISA kits for a wide range of species.
SEMA4D/CD100 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SEMA4D/CD100 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC, ELISA, ICC, Neut
Validations
- (7)
N° du produit
ABIN5611304
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN564579
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS
Validations
- (3)
N° du produit
ABIN7505849
Quantité
100 tests
Fiche technique
Fiche technique
SEMA4D/CD100 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6959355
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962543
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959356
Quantité
96 tests
Fiche technique
Fiche technique
SEMA4D/CD100 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275566
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275561
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275565
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SEMA4D/CD100
: "A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma." dans: Analytical biochemistry, Vol. 574, pp. 15-22, (2020) (PubMed).: "Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis. ..." dans: The Journal of allergy and clinical immunology, Vol. 145, Issue 3, pp. 843-854.e4, (2020) (PubMed).
: "Sema4D/PlexinB1 promotes endothelial differentiation of dental pulp stem cells via activation of AKT and ERK1/2 signaling." dans: Journal of cellular biochemistry, Vol. 120, Issue 8, pp. 13614-13624, (2019) (PubMed).
: "Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma." dans: Blood cancer journal, Vol. 8, Issue 5, pp. 42, (2019) (PubMed).
: "Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells." dans: Journal of endodontics, Vol. 43, Issue 2, pp. 297-305, (2018) (PubMed).
: "Sema4D/PlexinB1 inhibition ameliorates blood-brain barrier damage and improves outcome after stroke in rats." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 4, pp. 2181-2196, (2018) (PubMed).
: "Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index." dans: Obesity (Silver Spring, Md.), Vol. 25, Issue 4, pp. 794-800, (2017) (PubMed).
: "Interferon-α-induced CD100 on naïve CD8+ T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction." dans: The Journal of international medical research, Vol. 45, Issue 1, pp. 89-100, (2017) (PubMed).
: "Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment." dans: Expert opinion on therapeutic targets, pp. 1-8, (2014) (PubMed).
: "CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection." dans: PLoS ONE, Vol. 9, Issue 12, pp. e113338, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à SEMA4D/CD100
semaphorin 4D (Sema4d), semaphorin 4D (SEMA4D), sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d), C9orf164, CD100, coll-4, COLL-4, M-sema-G, Semacl2, SEMAJ, Semaj, Semcl2Protein level used designations for SEMA4D/CD100
- semaphorin-4D
- A8
- BB18
- GR3
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D
- M-sema G
- sema J
- semaphorin H
- semaphorin-C-like 2
- semaphorin-J
- semaphorin 4D
- collapsin-4
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