Septin 2 Produits
(Septin 2 (SEPT2))
Catégories
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (By similarity).
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Catégories Septin 2 en vedette
Septin 2 Anticorps
High quality antibodies with extensive validation data.
Septin 2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Septin 2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
N° du produit
ABIN308439
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN518271
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7168865
Quantité
100 μg
Fiche technique
Fiche technique
Septin 2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975081
Quantité
96 tests
Fiche technique
Fiche technique
Septin 2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125024
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319542
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319544
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Septin 2
: "Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins." dans: Oncotarget, Vol. 10, Issue 31, pp. 2959-2972, (2019) (PubMed).: "Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion." dans: The Journal of cell biology, Vol. 214, Issue 5, pp. 517-27, (2016) (PubMed).
: "Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion." dans: mBio, Vol. 5, Issue 5, pp. e01802-14, (2014) (PubMed).
: "Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol-resistant human breast cancer cell line MDA-MB-231." dans: Proteomics, Vol. 11, Issue 19, pp. 3877-86, (2011) (PubMed).
: "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7." dans: Cell, Vol. 130, Issue 5, pp. 837-50, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à Septin 2
septin 2 (SEPT2), septin 2 (Sept2), septin 2 (sept2), septin 2 L homeolog (sept2.L), septin 2-like (SEPT2L), COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain (sepT2), septin 2 S homeolog (sept2.S), AW208991, DIFF6, diff6, hNedd5, hnedd5, mKIAA0158, Nedd-5, NEDD5, Nedd5, nedd5, Pnutl3, pnutl3, Sep-02, sept2, SEPT2, sept2-B, septa, Septin-2, Septin-2A, Septin-2B, Septin-A, Vesp11, wu:fb52g01, wu:fb99a01, xlseptaProtein level used designations for Septin 2
- NEDD-5
- neural precursor cell expressed developmentally down-regulated protein 5
- neural precursor cell expressed, developmentally down-regulated 5
- septin-2
- neural precursor cell expressed, developmentally down-regulated gene 5
- vascular endothelial cell specific protein 11
- septin A
- septin-2A
- septin 2
- ANL34
- septin-2B
- Septin-2
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