(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008].
serpin A3-5 (LOC396684) Protéines serpin family A member 3 (SERPINA3) Protéines alpha-1-antiproteinase F precursor (LOC100008973) Protéines serpin family A member 1 (SERPINA1) Protéines serpin family A member 1 (Serpina1) Protéines serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) Protéines serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) Protéines serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog (serpina3.L) Protéines A1AT Protéines AACT Protéines AAT Protéines ACT Protéines alpha-1-PI Protéines GIG25 Protéines PI Protéines Pi Protéines Pi2 Protéines serpina3 Protéines SERPINA3-1 Protéines SERPINA3-5 Protéines Spi1 Protéines