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SERPINC1 Produits

(Serpin Family C Member 1 (SERPINC1))

Catégories

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009].

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Catégories SERPINC1 en vedette

SERPINC1 Anticorps

High quality antibodies with extensive validation data.

SERPINC1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SERPINC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SERPINC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7426502
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7429274
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7444019
Quantité 100 μL
Fiche technique Fiche technique

SERPINC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN6574304
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (3)
N° du produit ABIN6720495
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970109
Quantité 96 tests
Fiche technique Fiche technique

SERPINC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319632
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3088884
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3133739
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SERPINC1

Cheng, Xu, Yi, Sun, Yang, Yu, Yang, Jin, Tu, Zhang: "iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management." dans: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 1, pp. 216-232, (2019) (PubMed).

Verbree-Willemsen, Zhang, Gijsberts, Schoneveld, Wang, Lam, Vernooij, Bots, Peelen, Grobbee, Raichlen, de Kleijn: "LDL extracellular vesicle coagulation protein levels change after initiation of statin therapy. Findings from the METEOR trial." dans: International journal of cardiology, Vol. 271, pp. 247-253, (2019) (PubMed).

Wang, Zhang, Sze, van de Weg, Vernooij, Schoneveld, Tan, Versteeg, Timmers, Lam, de Kleijn: "Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles." dans: International journal of molecular sciences, Vol. 19, Issue 1, (2018) (PubMed).

Peltier, Roperch, Audebert, Borg, Camoin: "Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family." dans: Journal of proteomics, Vol. 148, pp. 139-48, (2016) (PubMed).

Gao, Ma, Liu, Teng, Wang, Su: "Thalidomide and multiple myeloma serum synergistically induce a hemostatic imbalance in endothelial cells in vitro." dans: Thrombosis research, Vol. 135, Issue 6, pp. 1154-9, (2015) (PubMed).

Kuusisto, Haapasaari, Remes, Bloigu, Karihtala, Turpeenniemi-Hujanen, Kuittinen: "Antithrombin III is probably not a suitable biomarker for diagnosis of primary central nervous system lymphoma." dans: Annals of hematology, Vol. 94, Issue 7, pp. 1167-74, (2015) (PubMed).

Wang, Yuan, Zhong, Wen, Deng, Liang, Zheng: "The anticoagulant effect of PGI2S and tPA in transgenic umbilical vein endothelial cells is linked to up-regulation of PKA and PKC." dans: International journal of molecular sciences, Vol. 15, Issue 2, pp. 2826-39, (2014) (PubMed).

Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." dans: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).

Bianchini, Fazavana, Picard, Borgel: "Development of a recombinant antithrombin variant as a potent antidote to fondaparinux and other heparin derivatives." dans: Blood, Vol. 117, Issue 6, pp. 2054-60, (2011) (PubMed).

Gardell, Krueger, Antrilli, Elokdah, Mayer, Orcutt, Crandall, Vlasuk: "Neutralization of plasminogen activator inhibitor I (PAI-1) by the synthetic antagonist PAI-749 via a dual mechanism of action." dans: Molecular pharmacology, Vol. 72, Issue 4, pp. 897-906, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à SERPINC1

serpin family C member 1 (SERPINC1), antithrombin-III (CpipJ_CPIJ000472), antithrombin-III (CpipJ_CPIJ013111), serpin family C member 1 (Serpinc1), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), AI114908, ANTITHROMBIN, AT-III, At-3, AT-III, AT3, At3, AT3D, ATIII, DKFZp470C1733, SERPINC1, THPH7

Protein level used designations for SERPINC1

  • antithrombin-III
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Antithrombin-III
  • anti-thrombin 3
  • antithrombin
  • serpin C1
  • serpin peptidase inhibitor, clade C, member 1
  • ATIII
  • antithrombin III
  • serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
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