SET Domain Containing (Lysine Methyltransferase) 8 Protéines
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
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custom-made
SETD8
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SETD8
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SETD8
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
1 image
SETD8
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
SETD8
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS
SETD8
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 85 %
SDS
custom-made
SETD8
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
SETD8
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Rockland 009-001-t28s
SETD8
Origine: Humain
Hôte: Insect cells (Sf9)
Recombinant
>85%
WB
Rockland Original
SETD8
Origine: Boeuf (Vache)
Hôte: Levure
Recombinant
> 90 %
ELISA
SETD8
Origine: Xenopus tropicalis
Hôte: Levure
Recombinant
> 90 %
ELISA
SETD8
Origine: Schizosaccharomyces pombe
Hôte: Levure
Recombinant
> 90 %
ELISA
Pseudonymes pour SET Domain Containing (Lysine Methyltransferase) 8 Protéines
lysine methyltransferase 5A (KMT5A) Protéineslysine methyltransferase 5A (Kmt5a) Protéines
lysine methyltransferase 5Ab (kmt5ab) Protéines
lysine methyltransferase 5A S homeolog (kmt5a.S) Protéines
lysine methyltransferase 5Aa (kmt5aa) Protéines
2410195B05Rik Protéines
AA617402 Protéines
AW536475 Protéines
KMT5A Protéines
kmt5a Protéines
kmt5a-a Protéines
PR-Set7 Protéines
PR-SET7 Protéines
Pr-set7 Protéines
RGD1305893 Protéines
SET07 Protéines
SET8 Protéines
set8a Protéines
Setd8 Protéines
setd8 Protéines
setd8-a Protéines
setd8a Protéines
setd8b Protéines
wu:fc23f12 Protéines
wu:fj33f02 Protéines
zgc:153719 Protéines
zgc:171649 Protéines
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