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SET Domain Containing (Lysine Methyltransferase) 8 Protéines

(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

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SETD8 Protein (AA 1-349) (His tag)

custom-made SETD8 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Kmt5a Protein, UniprotID Q2YDW7

3 images

N° du produit ABIN7563657

Détails

SETD8 Protein (AA 1-393) (His tag)

custom-made SETD8 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant KMT5A Protein, UniprotID Q9NQR1

3 images

N° du produit ABIN7554369

Détails

SETD8 Protein (AA 195-352) (His-IF2DI Tag)

SETD8 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) protein (His-IF2DI Tag) (ABIN7125068)

1 image

N° du produit ABIN7125068

Détails

SETD8 Protein (AA 226-393) (His-IF2DI Tag)

SETD8 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

N° du produit ABIN7665452

Détails

SETD8 Protein (His tag)

SETD8 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS

N° du produit ABIN7577828

Détails

SETD8 Protein (AA 195-352) (His tag)

SETD8 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS

N° du produit ABIN5855179

Détails

SETD8 Protein (AA 1-349) (Strep Tag)

custom-made SETD8 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3134954

Détails

SETD8 Protein (AA 1-393) (Strep Tag)

custom-made SETD8 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3093468