Chèvre anti-Rat IgG (Heavy & Light Chain) Anticorps

N° du produit ABIN102117

N° du produit (Fournisseur): 612-1102

Aperçu rapide pour Chèvre anti-Rat IgG (Heavy & Light Chain) Anticorps (ABIN102117)

Antigène: IgG

Clonalité: Polyclonal

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Isotype: IgG

Détail du produit

Épitope: Heavy & Light Chain

Reactivité: Rat

Hôte: Chèvre

N° du produit (Fournisseur): 612-1102

Fournisseur: Rockland

Fonction: Rat IgG (H&L) Antibody

Réactivité croisée (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum, Rat IgG and Rat Serum.

Attributs du produit: Anti-Rat IgG (H&L) Texas Red™ Antibody generated in goat detects reactivity to Rat IgG.

Purification: Anti-RAT IgG (H&L) (GOAT) Antibody was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgG coupled to agarose beads.

Stérilité: Sterile filtered

Immunogène: Optional[Immunogen]: Rat IgG whole molecule

Information d'application

Indications d'application: Application Note: Anti-RAT IgG (H&L) (GOAT) Antibody has been tested by ELISA and western blot and is suitable for Immunohistochemistry applications. Specific conditions for reactivity should be optimized by the end user. Immunohistochemistry Dilution: 1:1,000-1:5,000 Western Blot Dilution: 1:2,000-1:10,000 ELISA Dilution: 1:20,000-1:100,000 Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

, Preservative:0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. 

Date de péremption: 12 months

Référence

Scekic-Zahirovic, Oussini, Mersmann, Drenner, Wagner, Sun, Allmeroth, Dieterlé, Sinniger, Dirrig-Grosch, René, Dormann, Haass, Ludolph, Lagier-Tourenne, Storkebaum, Dupuis: "Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis." dans: Acta neuropathologica, Vol. 133, Issue 6, pp. 887-906, (2017) (PubMed).

Zhang, Fu, Chen, Ren, Qu, Zhang, Yao, Yang: "Lacidipine attenuates apoptosis via a caspase-3 dependent pathway in human kidney cells." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 32, Issue 4, pp. 1040-9, (2014) (PubMed).

Détail du antigène

Antigène: IgG

Classe de substances: Antibody

Sujet: Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75 % of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsonization for phagocytosis. The whole IgG molecule possesses both the F(c) region, recognized by high-affinity Fc receptor proteins, as well as the F(ab) region possessing the epitope-recognition site. Both the Heavy and Light chains of the antibody molecule are present. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition. Anti-rat IgG antibody is ideal for investigators involved in serum protein component research.