Souris anti-Humain IgE (Chain epsilon) Anticorps

N° du produit ABIN492638

Aperçu rapide pour Souris anti-Humain IgE (Chain epsilon) Anticorps (ABIN492638)

Antigène: IgE

Clonalité: Monoclonal

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Clone: HP6029

Isotype: IgG2a

Détail du produit

Épitope: Chain epsilon

Reactivité: Humain

Hôte: Souris

Purification: Purified

Information d'application

Indications d'application: ELISA. Western blottingDot- and slot-immunoblotting. Immunocytochemistry. Immunohistochemistry on Ffrozen Sections.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.

Agent conservateur: Without preservative

Conseil sur la manipulation: Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C

Détail du antigène

Antigène: IgE

Classe de substances: Antibody

Sujet: IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/mL, compared to 10 mg/mL for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.Synonyms: Immunoglobulin E human