Souris anti-Humain IgA (Free & Bound), (Secretory Component) Anticorps (Biotin)

N° du produit ABIN567756

Détail du produit

Antigène: IgA

Épitope: Free & Bound, Secretory Component

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Biotin

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Molar Ratio: Biotin/IgG: aprox. 1.4

Immunogène: Highly purified Secretory component isolated from Human milk.

Clone: NI 194-4 (A89-039)

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore by adding 0.5 mL sterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2

Concentration: 0.4 mg/mL

Buffer: PBS, pH 7.2 without preservatives. No foreign protein added.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated thawing and freezing. If a slight precipitation occurs upon storage, this should be removed by centrifugation.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody lyophilized at 2-8 °C for one month or (in aliquots) at -28 °C for longer. Diluted ascites should be stored at 2-8 °C, not refrozen, and preferably used the same day.

Détail du antigène

Antigène: IgA

Abstract: IgA Produits

Classe de substances: Antibody

Sujet: Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A