Souris anti-Humain IgA (Free & Bound), (Secretory Component) Anticorps

N° du produit ABIN567760

Aperçu rapide pour Souris anti-Humain IgA (Free & Bound), (Secretory Component) Anticorps (ABIN567760)

Antigène: IgA

Clonalité: Monoclonal

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: NI 194-4 (A89-039)

Isotype: IgG1

Détail du produit

Épitope: Free & Bound, Secretory Component

Reactivité: Humain

Hôte: Souris

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ascites

Immunogène: Highly purified Secretory component isolated from Human milk.

Information d'application

Indications d'application: General Recommended Dilutions:
Histochemical Use: from 1/50-1/200.
ELISA: form 1/500 upwards.
Western blot: from 1/1000 upwards.


Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore by adding 0.5 mL sterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2

Concentration: 1.0 mg/mL

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.

Détail du antigène

Antigène: IgA

Classe de substances: Antibody

Sujet: Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A