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Souris anti-Humain IgA (Free & Bound), (Secretory Component) Anticorps

WB, IF, IHC (fro), IP, EIA Monoclonal NI 194-4 (A89-039) IgG1 unconjugated
N° du produit ABIN567760
  • Antigène Tous les produits IgA
    IgA
    Épitope
    • 105
    • 60
    • 38
    • 15
    • 14
    • 12
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Free & Bound, Secretory Component
    Reactivité
    • 160
    • 58
    • 44
    • 16
    • 16
    • 14
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 201
    • 98
    • 49
    • 17
    • 12
    • 6
    • 2
    Souris
    Clonalité
    • 308
    • 62
    Monoclonal
    Application
    • 182
    • 136
    • 130
    • 111
    • 100
    • 96
    • 55
    • 39
    • 39
    • 28
    • 28
    • 24
    • 23
    • 18
    • 17
    • 17
    • 17
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Ascites
    Immunogène
    Highly purified Secretory component isolated from Human milk.
    Clone
    NI 194-4 (A89-039)
    Isotype
    IgG1
  • Indications d'application
    General Recommended Dilutions:
    Histochemical Use: from 1/50-1/200.
    ELISA: form 1/500 upwards.
    Western blot: from 1/1000 upwards.


    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore by adding 0.5 mL sterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2
    Concentration
    1.0 mg/mL
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • Antigène
    IgA
    Abstract
    IgA Produits
    Classe de substances
    Antibody
    Sujet
    Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
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