Recombinant Lapin anti-Humain IgD Anticorps

N° du produit ABIN7828298

Aperçu rapide pour Recombinant Lapin anti-Humain IgD Anticorps (ABIN7828298)

Antigène: IgD

Type d'anticorp: Recombinant Antibody

Clonalité: Monoclonal

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone: A258

Isotype: IgG, kappa

Détail du produit

Reactivité: Humain

Hôte: Lapin

Fonction: Recombinant Human IgD Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Human IgD fragment

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IgD

Classe de substances: Antibody

Sujet: IGHD,IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 42 kDa

Observed MW: 75 kDa The actual band is not consistent with the expectation.

UniProt: P01880