Souris anti-Humain IgE Anticorps

N° du produit ABIN94399

Aperçu rapide pour Souris anti-Humain IgE Anticorps (ABIN94399)

Antigène: IgE

Clonalité: Monoclonal

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Clone: 4H10

Isotype: IgG1

Détail du produit

Reactivité: Humain

Hôte: Souris

Fonction: Anti-Hu IgE Purified

Réactivité croisée (Details): Human

Attributs du produit: The mouse monoclonal antibody 4H10 reacts with human IgE, it recognizes an epitope different from the ones recognized by BE5 and 4G7.325 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Purified human IgE.

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 4 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détail du antigène

Antigène: IgE

Sujet: Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E

Poids moléculaire: 180 kDa

ID gène: 35