SHMT1 Produits
(serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
Catégories
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Catégories SHMT1 en vedette
SHMT1 Anticorps
High quality antibodies with extensive validation data.
SHMT1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SHMT1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SHMT1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (7)
N° du produit
ABIN562870
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN7256154
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN6147744
Quantité
100 μL
Fiche technique
Fiche technique
SHMT1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959375
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1156948
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1156949
Quantité
96 tests
Fiche technique
Fiche technique
SHMT1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319951
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319953
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125034
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SHMT1
: "Suppression by TFR cells leads to durable and selective inhibition of B cell effector function." dans: Nature immunology, Vol. 17, Issue 12, pp. 1436-1446, (2016) (PubMed).: "cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions." dans: Cell research, Vol. 25, Issue 4, pp. 429-44, (2015) (PubMed).
: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." dans: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).
: "Folate polyglutamylation eliminates dependence of activity on enzyme concentration in mitochondrial serine hydroxymethyltransferases from Arabidopsis thaliana." dans: Archives of biochemistry and biophysics, Vol. 536, Issue 1, pp. 87-96, (2013) (PubMed).
: "Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis." dans: PLoS genetics, Vol. 8, Issue 3, pp. e1002573, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à SHMT1
serine hydroxymethyltransferase 1 (Shmt1), serine hydroxymethyltransferase 1 (soluble) L homeolog (shmt1.L), serine hydroxymethyltransferase 1 (soluble) (shmt1), microRNA 6778 (MIR6778), serine hydroxymethyltransferase 1 (SHMT1), serine hydroxymethyltransferase 1 (soluble) (Shmt1), serine transhydroxymethyltransferase 1 (SHM1), AI324848, AI385541, C81125, CSHMT, F20D10.50, F20D10_50, LRRGT00032, MEL-32, MGC53442, mShmt, mshmt, mshmt1, mshmt2, SERINE HYDROXYMETHYLTRANSFERASE 1, SERINE TRANSHYDROXYMETHYLASE, SERINE TRANSHYDROXYMETHYLTRANSFERASE, serine transhydroxymethyltransferase 1, Shmt, SHMT, shmt1, SHMT1, Shmt1, SHMT2, STM, zgc:66171, zgc:77524Protein level used designations for SHMT1
- serine hydroxymethyltransferase, cytosolic
- serine hydroxymethyltransferase 1 (soluble)
- zSHMT-1
- SHMT
- glycine hydroxymethyltransferase
- serine methylase
- cytoplasmic serine hydroxymethyltransferase
- cytosolic serine hydroxymethyltransferase
- serine hydroxymethyl transferase
- serine hydroxymethyltransferase 2 (mitochondrial)
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