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SIP1 Produits

(Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Catégories

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011].

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Catégories SIP1 en vedette

SIP1 Anticorps

High quality antibodies with extensive validation data.

SIP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7010314
Quantité 60 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IHC (p)
Validations
  • (4)
N° du produit ABIN625932
Quantité 0.05 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IP
Validations
  • (3)
N° du produit ABIN7153753
Quantité 100 μg
Fiche technique Fiche technique

SIP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231037
Quantité 96 tests
Fiche technique Fiche technique

SIP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320025
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3080724
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3128349
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SIP1

Wiles, Bell, Thomas, Beckerle, Lessnick: "ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma." dans: Genes & cancer, Vol. 4, Issue 11-12, pp. 486-500, (2014) (PubMed).

Tange, Oktyabri, Terashima, Ishimura, Suzuki: "JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines." dans: PLoS ONE, Vol. 9, Issue 12, pp. e115684, (2014) (PubMed).

Sanchez, Dury, Murray, Biondi, Tadesse, El Fatimy, Kothary, Charbonnier, Khandjian, Côté: "A novel function for the survival motoneuron protein as a translational regulator." dans: Human molecular genetics, Vol. 22, Issue 4, pp. 668-84, (2013) (PubMed).

Wu, Whye, Glazewski, Choe, Kerr, Lee, Mason, Wang: "Proteomic assessment of a cell model of spinal muscular atrophy." dans: BMC neuroscience, Vol. 12, pp. 25, (2011) (PubMed).

Takizawa, Qing, Takaku, Ishida, Morozumi, Tsujita, Kogame, Hirota, Takahashi, Shibata, Kurumizaka, Takeda: "GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination." dans: Nucleic acids research, Vol. 38, Issue 15, pp. 5059-74, (2010) (PubMed).

Oztas, Avci, Ozcan, Sayan, Tulchinsky, Yagci: "Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays." dans: Experimental and molecular pathology, Vol. 89, Issue 2, pp. 182-9, (2010) (PubMed).

Burnett, Muñoz, Tandon, Kwon, Sumner, Fischbeck: "Regulation of SMN protein stability." dans: Molecular and cellular biology, Vol. 29, Issue 5, pp. 1107-15, (2009) (PubMed).

Walker, Rajendra, Saieva, Fuentes, Pellizzoni, Matera: "SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain." dans: Human molecular genetics, Vol. 17, Issue 21, pp. 3399-410, (2008) (PubMed).

Morency, Sabra, Catez, Texier, Lomonte: "A novel cell response triggered by interphase centromere structural instability." dans: The Journal of cell biology, Vol. 177, Issue 5, pp. 757-68, (2007) (PubMed).

Renvoisé, Khoobarry, Gendron, Cibert, Viollet, Lefebvre: "Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells." dans: Journal of cell science, Vol. 119, Issue Pt 4, pp. 680-92, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à SIP1

gem nuclear organelle associated protein 2 (GEMIN2), gem nuclear organelle associated protein 2 (Gemin2), gem (nuclear organelle) associated protein 2 (Gemin2), gem nuclear organelle associated protein 2 S homeolog (gemin2.S), gem (nuclear organelle) associated protein 2 (gemin2), 1700012N19Rik, SIP1, Sip1, sip1, SIP1-delta, sip1-delta, wu:fc52a05, zgc:110274

Protein level used designations for SIP1

  • SMN interacting protein 1-delta
  • component of gems 2
  • gem-associated protein 2
  • gemin-2
  • survival of motor neuron protein interacting protein 1
  • SMN-interacting protein 1
  • survival of motor neuron protein-interacting protein 1
  • survivor of motor neuron protein interacting protein 1
  • SMN interacting protein-1
  • Survival of motor neuron protein-interacting protein 1
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