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SLAMF6 Produits

(SLAM Family Member 6 (SLAMF6))

Catégories

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].

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Catégories SLAMF6 en vedette

SLAMF6 Anticorps

High quality antibodies with extensive validation data.

SLAMF6 Kits ELISA

Reliable ELISA kits for a wide range of species.

SLAMF6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLAMF6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (6)
N° du produit ABIN7193226
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7169782
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
N° du produit ABIN530287
Quantité 50 μL
Fiche technique Fiche technique

SLAMF6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884012
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6384208
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730057
Quantité 96 tests
Fiche technique Fiche technique

SLAMF6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275620
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275622
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275617
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SLAMF6

Joas, Parrish, Gnanadurai, Lump, Stürzel, Parrish, Learn, Sauermann, Neumann, Rensing, Fuchs, Billingsley, Bosinger, Silvestri, Apetrei, Huot, Garcia-Tellez, Müller-Trutwin, Hotter, Sauter et al.: "Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 1371, (2018) (PubMed).

Davis, Sowrirajan, Cogswell, Ward, Planelles, Barker: "CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells." dans: AIDS research and human retroviruses, Vol. 33, Issue 2, pp. 93-100, (2017) (PubMed).

Kmiec, Iyer, Stürzel, Sauter, Hahn, Kirchhoff: "Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance." dans: mBio, Vol. 7, Issue 4, (2016) (PubMed).

Sullivan, Jeha, Kang, Cheng, Rooney, Holladay, Bari, Schell, Tuggle, Pui, Leung: "NK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 5986-94, (2014) (PubMed).

Proust, Bertoglio, Gesbert: "The adaptor protein SAP directly associates with CD3? chain and regulates T cell receptor signaling." dans: PLoS ONE, Vol. 7, Issue 8, pp. e43200, (2012) (PubMed).

Hislop, Palendira, Leese, Arkwright, Rohrlich, Tangye, Gaspar, Lankester, Moretta, Rickinson: "Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets." dans: Blood, Vol. 116, Issue 17, pp. 3249-57, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." dans: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Matesanz-Isabel, Sintes, Llinàs, de Salort, Lázaro, Engel: "New B-cell CD molecules." dans: Immunology letters, Vol. 134, Issue 2, pp. 104-12, (2010) (PubMed).

Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: "The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia." dans: Blood, Vol. 114, Issue 18, pp. 3822-30, (2009) (PubMed).

Banerjee, Feuer, Barker et al.: "Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and reduces adherence of natural killer cells, thereby protecting HTLV-1-infected primary CD4+ T cells from autologous ..." dans: Journal of virology, Vol. 81, Issue 18, pp. 9707-17, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à SLAMF6

SLAM family member 6 (SLAMF6), SLAM family member 6 (Slamf6), CD352, KAL1, KAL1b, KALI, KALIb, Ly108, NTB-A, NTBA, RGD1561848, SF2000, SLAMF6

Protein level used designations for SLAMF6

  • SLAM family member 6
  • activating NK receptor
  • NK-T-B-antigen
  • NTBA receptor
  • natural killer-, T- and B-cell antigen
  • lymphocyte antigen 108
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