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SLCO1B1 Produits

(Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Catégories

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009].

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Catégories SLCO1B1 en vedette

SLCO1B1 Anticorps

High quality antibodies with extensive validation data.

SLCO1B1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLCO1B1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7170287
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (3)
N° du produit ABIN6257509
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN653562
Quantité 400 μL
Fiche technique Fiche technique

SLCO1B1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320553
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3077187
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3119575
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SLCO1B1

Green, Kaipainen, Bullock, Zhang, Lucas, Matson, Banks, Mostaghel: "Role of OATP transporters in steroid uptake by prostate cancer cells in vivo." dans: Prostate cancer and prostatic diseases, (2016) (PubMed).

Hogg, Thomas, Ashford, Cartwright, Coldwell, Weston, Pillmoor, Surry, OToole: "Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry." dans: Methods (San Diego, Calif.), Vol. 82, pp. 38-46, (2015) (PubMed).

Ramsey, Bruun, Yang, Treviño, Vattathil, Scheet, Cheng, Rosner, Giacomini, Fan, Sparreboom, Mikkelsen, Corydon, Pui, Evans, Relling: "Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition." dans: Genome research, Vol. 22, Issue 1, pp. 1-8, (2012) (PubMed).

Leuthold, Hagenbuch, Mohebbi, Wagner, Meier, Stieger: "Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C570-82, (2009) (PubMed).

Yamaguchi, Okada, Akitaya, Ohara, Mikkaichi, Ishikawa, Sato, Matsuura, Saga, Unno, Abe, Mano, Hishinuma, Goto: "Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3." dans: Journal of lipid research, Vol. 47, Issue 6, pp. 1196-202, (2006) (PubMed).

Cui, König, Nies, Pfannschmidt, Hergt, Franke, Alt, Moll, Keppler: "Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 4, pp. 527-38, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à SLCO1B1

solute carrier organic anion transporter family member 1B1 (SLCO1B1), solute carrier organic anion transporter family member 1B1 (LOC100011628), solute carrier organic anion transporter family member 1B1 (LOC100448597), HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6, SLCO1B1

Protein level used designations for SLCO1B1

  • OATP-2
  • liver-specific organic anion transporter 1
  • sodium-independent organic anion-transporting polypeptide 2
  • solute carrier family 21 (organic anion transporter), member 6
  • solute carrier family 21 member 6
  • solute carrier organic anion transporter family member 1B1
  • solute carrier organic anion transporter family, member 1B1
  • solute carrier organic anion transporter family member 1B1-like
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