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SMO Produits

(Smoothened Homolog (Drosophila) (SMO))
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010].

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Catégories SMO en vedette

SMO Anticorps

High quality antibodies with extensive validation data.

SMO Kits ELISA

Reliable ELISA kits for a wide range of species.

SMO Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SMO recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (p)
Validations
  • (3)
  • (4)
N° du produit ABIN680908
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN6148140
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7169898
Quantité 100 μg
Fiche technique Fiche technique

SMO recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959535
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959536
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Sandwich ELISA
Validations
N° du produit ABIN418558
Quantité 96 tests
Fiche technique Fiche technique

SMO recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3077343
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3120518
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3120520
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SMO

Zhou, Zhou, Liu, Shen: "GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment." dans: Scientific reports, Vol. 7, Issue 1, pp. 13379, (2019) (PubMed).

Wang, Zhang, Bai, Wang, Du: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, (2016) (PubMed).

Lu, Ma, Mao, Yu, Hou, Fan, Song, Wang, Li, Kang, Liu, Liu, Li: "Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling." dans: Chemico-biological interactions, Vol. 228, pp. 100-7, (2015) (PubMed).

Sweeney, McClary, Myers, Biscocho, Neahring, Kwei, Qu, Gong, Ng, Jones, Varma, Odegaard, Sugiyama, Koyota, Rubin, Troxell, Pelham, Zehnder, Beachy, Pollack, West: "Identification of recurrent SMO and BRAF mutations in ameloblastomas." dans: Nature genetics, Vol. 46, Issue 7, pp. 722-5, (2014) (PubMed).

Zhang, He, Zhang, Li, Yue, Wang, Jablons, He, Lui: "SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma." dans: Journal of experimental & clinical cancer research : CR, Vol. 32, pp. 7, (2013) (PubMed).

Wang, Wu, Katritch, Han, Huang, Liu, Siu, Roth, Cherezov, Stevens: "Structure of the human smoothened receptor bound to an antitumour agent." dans: Nature, Vol. 497, Issue 7449, pp. 338-43, (2013) (PubMed).

Rana, Carroll, Lee, Bao, Marada, Grace, Guibao, Ogden, Zheng: "Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling." dans: Nature communications, Vol. 4, pp. 2965, (2013) (PubMed).

Tao, Mao, Zhang, Li: "Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer." dans: Oncology letters, Vol. 2, Issue 5, pp. 995-1001, (2012) (PubMed).

Bolaños, Milla, Lira, Ramírez, Checa, Barrera, García-Alvarez, Carbajal, Becerril, Gaxiola, Pardo, Selman: "Role of Sonic Hedgehog in idiopathic pulmonary fibrosis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 303, Issue 11, pp. L978-90, (2012) (PubMed).

Walter, Omura, Hong, Griffith, Vincent, Borges, Goggins: "Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 6, pp. 1781-9, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à SMO

smoothened, frizzled class receptor (SMO), smoothened, frizzled class receptor (Smo), smoothened, frizzled class receptor L homeolog (smo.L), smoothened, frizzled class receptor (smo), bnb, E130215L21Rik, FZD11, Gx, SMOH, Smoh, smoothened, XSmo

Protein level used designations for SMO

  • frizzled family member 11
  • protein Gx
  • seven transmembrane helix receptor
  • smoothened homolog
  • smoothened, seven transmembrane spanning receptor
  • bent body
  • X-smoothened
  • smoothened, frizzled family receptor
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