SOCS1 Produits
(Suppressor of Cytokine Signaling 1 (SOCS1))
Catégories
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008].
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Catégories SOCS1 en vedette
SOCS1 Anticorps
High quality antibodies with extensive validation data.
SOCS1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SOCS1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SOCS1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (6)
N° du produit
ABIN6148263
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC, IF, FACS
Validations
- (11)
N° du produit
ABIN184575
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, IF, IHC (p), FACS
Validations
- (5)
N° du produit
ABIN652738
Quantité
400 μL
Fiche technique
Fiche technique
SOCS1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959764
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970479
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970477
Quantité
96 tests
Fiche technique
Fiche technique
SOCS1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (3)
N° du produit
ABIN3131672
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125254
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125253
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SOCS1
: "Poor stimulation of bovine dendritic cells by Mycobacterium bovis culture supernatant and surface extract is associated with decreased activation of ERK and NF-κB and higher expression of SOCS1 and 3." dans: Innate immunity, Vol. 26, Issue 6, pp. 537-546, (2020) (PubMed).: "Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis." dans: Frontiers in cellular and infection microbiology, Vol. 7, pp. 443, (2018) (PubMed).
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." dans: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).
: "Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model." dans: European journal of pharmacology, Vol. 793, pp. 119-126, (2017) (PubMed).
: "MicroRNA-155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th17) cells." dans: Clinical and experimental immunology, Vol. 181, Issue 1, pp. 142-9, (2015) (PubMed).
: "TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection." dans: Neurobiology of disease, Vol. 69, pp. 235-47, (2014) (PubMed).
: "The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1." dans: Cell death & disease, Vol. 5, pp. e1061, (2014) (PubMed).
: "SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor." dans: PLoS ONE, Vol. 8, Issue 9, pp. e76370, (2013) (PubMed).
: "IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology." dans: Cell, Vol. 144, Issue 4, pp. 601-13, (2011) (PubMed).
: "Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia." dans: Nature medicine, Vol. 17, Issue 7, pp. 845-53, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à SOCS1
suppressor of cytokine signaling 1a (socs1a), suppressor of cytokine signaling 1 (socs1), suppressor of cytokine signaling 1 (SOCS1), suppressor of cytokine signaling 1 L homeolog (socs1.L), suppressor of cytokine signaling 1 (Socs1), cis1, CIS1, cish1, CISH1, Cish1, Cish7, jab, JAB, LOC100228306, socs-1, SOCS-1, Socs-1, socs1, SOCS1, socs1b, ssi-1, SSI-1, ssi1, SSI1, tip3, TIP3, zgc:91868Protein level used designations for SOCS1
- suppressor of cytokine signaling 1
- suppressor of cytokine signalling
- suppressor of cytokine signaling 1b
- suppressor of cytokine signaling 1-like protein
- JAK binding protein
- JAK-binding protein
- STAT induced SH3 protein 1
- STAT-induced STAT inhibitor 1
- TIP-3
- Tec-interacting protein 3
- cytokine-inducible SH2 protein 1
- JAK2-binding protein
- cytokine inducible SH2-containing protein 1
- cytokine inducible SH2-containing protein 7
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