SOS1 Produits
(Son of Sevenless Homolog 1 (SOS1))
Catégories
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008].
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Catégories SOS1 en vedette
SOS1 Anticorps
High quality antibodies with extensive validation data.
SOS1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SOS1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (4)
N° du produit
ABIN7170318
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, PLA
Validations
- (4)
N° du produit
ABIN520376
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Dog, Human, Mouse, Rat
Application
WB, IF, IP, IHC
Validations
- (5)
- (2)
N° du produit
ABIN967741
Quantité
150 μg
Fiche technique
Fiche technique
SOS1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970366
Quantité
96 tests
Fiche technique
Fiche technique
SOS1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320973
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3095504
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3135535
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SOS1
: "Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes." dans: The Journal of biological chemistry, Vol. 283, Issue 5, pp. 2465-9, (2008) (PubMed).: "GEFs in growth factor signaling." dans: Growth factors (Chur, Switzerland), Vol. 25, Issue 5, pp. 355-61, (2008) (PubMed).
: "Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1." dans: Archives of biochemistry and biophysics, Vol. 479, Issue 1, pp. 52-62, (2008) (PubMed).
: "Effects of SHIP-1 on MMP2 secretion and invasion of SR3Y1 cells." dans: Journal of genetics and genomics = Yi chuan xue bao, Vol. 34, Issue 4, pp. 285-93, (2007) (PubMed).
: "T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11382-7, (2007) (PubMed).
: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." dans: Oncogene, Vol. 21, Issue 46, pp. 7060-6, (2002) (PubMed).
: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." dans: Blood, Vol. 98, Issue 6, pp. 1773-81, (2001) (PubMed).
: "ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells." dans: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5966-75, (2000) (PubMed).
: "Signaling from Ras to Rac and beyond: not just a matter of GEFs." dans: The EMBO journal, Vol. 19, Issue 11, pp. 2393-8, (2000) (PubMed).
: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." dans: Cell, Vol. 73, Issue 3, pp. 611-20, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1 (SOS1), son of sevenless homolog 1 (Drosophila) (Sos1), SOS Ras/Rac guanine nucleotide exchange factor 1 (Sos1), 4430401P03Rik, 9630010N06, AI449023, GF1, GGF1, GINGF, HGF, NS4Protein level used designations for SOS1
- SOS-1
- gingival fibromatosis, hereditary, 1
- guanine nucleotide exchange factor
- son of sevenless homolog 1
- guanine nucleotide releasing factor
- ras guanine exchange factor
- son-of-sevenless 1
- Son of sevenless homolog 1
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