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SP100 Produits

(SP100 Nuclear Antigen (SP100))

Catégories

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011].

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Catégories SP100 en vedette

SP100 Anticorps

High quality antibodies with extensive validation data.

SP100 Kits ELISA

Reliable ELISA kits for a wide range of species.

SP100 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SP100 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7442741
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (4)
N° du produit ABIN562971
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (3)
N° du produit ABIN948494
Quantité 50 μg
Fiche technique Fiche technique

SP100 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN511609
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN775695
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN777660
Quantité 96 tests
Fiche technique Fiche technique

SP100 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321019
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321021
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3131693
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SP100

Niu, Livingston, Li, Beran, Daffis, Ramakrishnan, Burdette, Peiser, Salas, Ramos, Yu, Cheng, Strubin, Delaney Iv, Fletcher: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).

Berard, Coombs, Severini: "Quantification of the host response proteome after herpes simplex virus type 1 infection." dans: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).

Wagenknecht, Reuter, Scherer, Reichel, Müller, Stamminger: "Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1." dans: Viruses, Vol. 7, Issue 6, pp. 2884-907, (2015) (PubMed).

Full, Jungnickl, Reuter, Bogner, Brulois, Scholz, Stürzl, Myoung, Jung, Stamminger, Ensser: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." dans: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).

Stepp, Meyers, McBride: "Sp100 provides intrinsic immunity against human papillomavirus infection." dans: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).

Adler, Tavalai, Müller, Stamminger: "Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100." dans: The Journal of general virology, Vol. 92, Issue Pt 7, pp. 1532-8, (2011) (PubMed).

Tavalai, Adler, Scherer, Riedl, Stamminger: "Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle." dans: Journal of virology, Vol. 85, Issue 18, pp. 9447-58, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à SP100

SP100 nuclear antigen (SP100), nuclear antigen Sp100 (Sp100), SP100 nuclear antigen (Sp100), nuclear autoantigen Sp-100 (LOC101120993), A430075G10Rik, lysp100b, SP100, SP140

Protein level used designations for SP100

  • SP100 nuclear antigen
  • nuclear autoantigen Sp-100
  • nuclear autoantigen Sp-100-like
  • nuclear dot-associated Sp100 protein
  • speckled 100 kDa
  • SP100-HMG nuclear autoantigen
  • nuclear antigen Sp100
  • Nuclear autoantigen Sp-100
  • SP140 nuclear body protein
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