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SPANXB1 Produits

(SPANX Family, Member B1 (SPANXB1))

Catégories

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008].

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Catégories SPANXB1 en vedette

SPANXB1 Anticorps

High quality antibodies with extensive validation data.

SPANXB1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
  • (1)
N° du produit ABIN1881824
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN531836
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN531837
Quantité 200 μL
Fiche technique Fiche technique

SPANXB1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6234137
Quantité 96 tests
Fiche technique Fiche technique

SPANXB1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321076
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3077380
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SPANXB1

Hansen, Eichler, Fullerton, Carrell: "SPANX gene variation in fertile and infertile males." dans: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).

Hansen, Nielsen, Retelska, Larsen, Leffers: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." dans: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).

Kouprina, Pavlicek, Noskov, Solomon, Otstot, Isaacs, Carpten, Trent, Schleutker, Barrett, Jurka, Larionov: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." dans: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).

Zendman, Zschocke, van Kraats, de Wit, Kurpisz, Weidle, Ruiter, Weiss, van Muijen: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." dans: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à SPANXB1

SPANX family member B1 (SPANXB1), B1, CT11.2, SPANX-B, SPANXB

Protein level used designations for SPANXB1

  • SPANX family member B/F
  • cancer/testis antigen 11.2
  • cancer/testis antigen family 11, member 2
  • nuclear-associated protein SPAN-Xb
  • nuclear-associated protein SPAN-Xf
  • sperm protein associated with the nucleus on the X chromosome B/F
  • sperm protein associated with the nucleus, X chromosome, family member B1
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