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SUCNR1 Produits

(Succinate Receptor 1 (SUCNR1))
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009].

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Catégories SUCNR1 en vedette

SUCNR1 Anticorps

High quality antibodies with extensive validation data.

SUCNR1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SUCNR1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SUCNR1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB, IF, IHC
Validations
  • (4)
N° du produit ABIN7170906
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application IHC (p), IHC
Validations
  • (2)
N° du produit ABIN1048897
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, IF, ICC
Validations
  • (2)
N° du produit ABIN6265363
Quantité 100 μL
Fiche technique Fiche technique

SUCNR1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1159995
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1159996
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1159997
Quantité 96 tests
Fiche technique Fiche technique

SUCNR1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3106209
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3128076
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
N° du produit ABIN1330532
Quantité 2 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SUCNR1

Wu, Huang, Hsieh, Wang, Yen, Lee, Yeh, Peng, Kuo, Wen, Lin, Hsiao, Wu, Kung, Hsu, Kuo: "Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor." dans: Molecular cell, Vol. 77, Issue 2, pp. 213-227.e5, (2020) (PubMed).

Caielli, Veiga, Balasubramanian, Athale, Domic, Murat, Banchereau, Xu, Chandra, Chung, Walters, Baisch, Wright, Punaro, Nassi, Stewart, Fuller, Ucar, Ueno, Zhou, Banchereau, Pascual: "A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate." dans: Nature medicine, Vol. 25, Issue 1, pp. 75-81, (2019) (PubMed).

Wang, Xu, Yuan, Xu, Zhang, Li, Wang, Yin, Zhang, Cai, Zhu, Xu, Liang, Schaul, Xie, Yue, Liao, Yu, Luo, Zhou, Yang, He, Du, Zhou, Deng, Wang, Gao, Zhu, Xi, Zhang, Shu, Jiang: "Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling." dans: EMBO reports, Vol. 20, Issue 9, pp. e47892, (2019) (PubMed).

Nguyen, Park, Le, Park, Choi, Cho: "Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition." dans: Biochemical and biophysical research communications, Vol. 495, Issue 4, pp. 2649-2656, (2018) (PubMed).

Peruzzotti-Jametti, Bernstock, Vicario, Costa, Kwok, Leonardi, Booty, Bicci, Balzarotti, Volpe, Mallucci, Manferrari, Donegà, Iraci, Braga, Hallenbeck, Murphy, Edenhofer, Frezza, Pluchino: "Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation." dans: Cell stem cell, Vol. 22, Issue 3, pp. 355-368.e13, (2018) (PubMed).

Mu, Zhao, Xu, Shi, Geng, Shen, Zhang, Pan, Yang, Hu, Lv, Wen, You: "Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation." dans: Oncotarget, Vol. 8, Issue 8, pp. 13174-13185, (2017) (PubMed).

Guo, Xie, Li, Yang, Yu, Zhang, Zhang, Saxena, Snyder, Wu, Li: "Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis." dans: Nature communications, Vol. 8, pp. 15621, (2017) (PubMed).

McCreath, Espada, Gálvez, Benito, de Molina, Sepúlveda, Cervera: "Targeted disruption of the SUCNR1 metabolic receptor leads to dichotomous effects on obesity." dans: Diabetes, Vol. 64, Issue 4, pp. 1154-67, (2015) (PubMed).

Hu, Li, Du, Chen, Wang, Xiong, Wu: "The MAPK signaling pathway mediates the GPR91-dependent release of VEGF from RGC-5 cells." dans: International journal of molecular medicine, Vol. 36, Issue 1, pp. 130-8, (2015) (PubMed).

Li, Hu, Du, Chen, Wang, Wu: "ERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes." dans: Molecular vision, Vol. 20, pp. 1109-21, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à SUCNR1

succinate receptor 1 (SUCNR1), succinate receptor 1 (Sucnr1), GPR91, Gpr91

Protein level used designations for SUCNR1

  • G protein-coupled receptor 91
  • G-protein coupled receptor 91
  • P2Y purinoceptor 1
  • succinate receptor 1
  • G-protein-coupled receptor 91
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