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TDP1 Protéines

(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].

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TDP1 Protein (AA 1-609) (His tag)

custom-made TDP1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Tdp1 Protein, UniprotID Q8BJ37

3 images

N° du produit ABIN7564369

Détails

TDP1 Protein (AA 1-608) (His tag)

custom-made TDP1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant TDP1 Protein, UniprotID Q9NUW8

3 images

N° du produit ABIN7555891

Détails

TDP1 Protein (AA 1-608) (GST tag)

TDP1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (GST tag) (ABIN1322434)

1 image

1 reference

N° du produit ABIN1322434

Détails

TDP1 Protéine

TDP1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS

Figure annotation denotes ug of protein loaded and % gel used.

SDS

1 image

N° du produit ABIN2132102

Détails

TDP1 Protein (AA 1-608) (His tag)

TDP1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS

SDS-PAGE (SDS) image for Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (His tag) (ABIN7281254)

SDS

1 image

N° du produit ABIN7281254

Détails

TDP1 Protein (AA 4-215) (His tag,GST tag)

TDP1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

N° du produit ABIN7419694

Détails

TDP1 Protein (AA 1-271) (His tag,GST tag)

TDP1 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant >90 % SDS, WB, Imm, PC

N° du produit ABIN7420363

Détails

TDP1 Protein (AA 1-151) (His tag)

TDP1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

N° du produit ABIN7423144

Détails

TDP1 Protein (AA 1-609) (Strep Tag)

custom-made TDP1 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3136184

Détails

TDP1 Protein (AA 1-608) (Strep Tag)

custom-made TDP1 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3096148