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TIM3 Produits

(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011].

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Catégories TIM3 en vedette

TIM3 Anticorps

High quality antibodies with extensive validation data.

TIM3 Kits ELISA

Reliable ELISA kits for a wide range of species.

TIM3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TIM3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, ELISA, IF
Validations
  • (8)
N° du produit ABIN185571
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, Coat, StM
Validations
  • (5)
N° du produit ABIN6940963
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (5)
  • (3)
N° du produit ABIN1881402
Quantité 400 μL
Fiche technique Fiche technique

TIM3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956490
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956491
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5692220
Quantité 96 tests
Fiche technique Fiche technique

TIM3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275736
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275739
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275740
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TIM3

Wu, Li, Xia, Tian, Kong, Wang, Gu, Zhang, Tu, Xie, Yang, Lu, Jiang, Ying: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." dans: Cell host & microbe, (2020) (PubMed).

Yang, Ying, Wu, Chen: "sTim-3 alleviates liver injury via regulation of the immunity microenvironment and autophagy." dans: Cell death discovery, Vol. 6, pp. 62, (2020) (PubMed).

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." dans: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Das, Choudhury, Jagadeeshaprasad, Kulkarni, Mondal, Bandyopadhyay: "Proteomic analysis detects deregulated reverse cholesterol transport in human subjects with ST-segment elevation myocardial infarction." dans: Journal of proteomics, Vol. 222, pp. 103796, (2020) (PubMed).

Franchini, Lanvin, Tosolini, Patras de Campaigno, Cammas, Péricart, Scarlata, Lebras, Rossi, Ligat, Pont, Arimondo, Laurent, Ayyoub, Despas, Lapeyre-Mestre, Millevoi, Fournié: "Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells." dans: Cell reports, Vol. 26, Issue 1, pp. 94-107.e7, (2019) (PubMed).

Wingrove, Liu, Patel, Arnal-Estapé, Cai, Melnick, Politi, Monteiro, Zhu, Valiente, Kluger, Chiang, Nguyen: "Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis." dans: Cell reports, Vol. 27, Issue 4, pp. 1277-1292.e7, (2019) (PubMed).

Klebanoff, Crompton, Leonardi, Yamamoto, Chandran, Eil, Sukumar, Vodnala, Hu, Ji, Clever, Black, Gurusamy, Kruhlak, Jin, Stroncek, Gattinoni, Feldman, Restifo: "Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy." dans: JCI insight, Vol. 2, Issue 23, (2018) (PubMed).

Wang, Edilova, Wagar, Mujib, Singer, Bernard, Croughs, Lederman, Sereti, Fischl, Kremmer, Ostrowski, Routy, Watts: "Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 558-564, (2018) (PubMed).

Roboz, Ritchie, Dault, Lam, Marshall, Cruz, Hsu, Hassane, Christos, Ippoliti, Scandura, Guzman: "Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia." dans: Haematologica, Vol. 103, Issue 8, pp. 1308-1316, (2018) (PubMed).

DAngelo, Melchiori, Merchant, Bernstein, Glod, Kaplan, Grupp, Tap, Chagin, Binder, Basu, Lowther, Wang, Bath, Tipping, Betts, Ramachandran, Navenot, Zhang, Wells, Van Winkle, Kari, Trivedi, Holdich et al.: "Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma. ..." dans: Cancer discovery, Vol. 8, Issue 8, pp. 944-957, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à TIM3

hepatitis A virus cellular receptor 2 (HAVCR2), hepatitis A virus cellular receptor 2 (Havcr2), HAVcr-2, HAVCR2, KIM-3, MGC140131, Tim-3, TIM-3, TIM3, Tim3, tim3, TIMD-3, TIMD3, Timd3

Protein level used designations for TIM3

  • hepatitis A virus cellular receptor 2
  • T cell immunoglobulin mucin 3
  • T cell immunoglobulin mucin-3
  • T-cell immunoglobulin and mucin domain-containing protein 3
  • T-cell membrane protein 3
  • kidney injury molecule-3
  • HAVcr-2
  • T-cell immunoglobulin and mucin domain containing 3
  • TIMD-3
  • hepatitis A virus cellular receptor 2 homolog
  • TIM-3
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