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TIMP1 Produits

(TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Catégories

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008].

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Catégories TIMP1 en vedette

TIMP1 Anticorps

High quality antibodies with extensive validation data.

TIMP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

TIMP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TIMP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (9)
  • (4)
N° du produit ABIN668331
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), IF, FACS
Validations
  • (5)
N° du produit ABIN655149
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), IF, FACS
Validations
  • (1)
  • (4)
N° du produit ABIN390664
Quantité 400 μL
Fiche technique Fiche technique

TIMP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (2)
  • (1)
N° du produit ABIN365420
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6959986
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
N° du produit ABIN6959987
Quantité 96 tests
Fiche technique Fiche technique

TIMP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275738
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275742
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7320879
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TIMP1

Duda, Krzych, Jędrzejowska-Szypułka, Lewin-Kowalik: "Plasma Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 as Prognostic Biomarkers in Critically Ill Patients." dans: Open medicine (Warsaw, Poland), Vol. 15, pp. 50-56, (2020) (PubMed).

Duda, Wiórek, Krzych: "Biomarkers Facilitate the Assessment of Prognosis in Critically Ill Patients with Primary Brain Injury: A Cohort Study." dans: International journal of environmental research and public health, Vol. 17, Issue 12, (2020) (PubMed).

Kudelski, Młynarczyk, Darewicz, Bruczko-Goralewska, Romanowicz: "Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity." dans: Medicine, Vol. 99, Issue 7, pp. e19224, (2020) (PubMed).

Le, Cao, Zhou, Fan, Liu, Liu, Gai, Chang, Xiong, Rao, Li, Xu, Liu, Wang, Wang, Sun: "Infection of Mycobacterium tuberculosis Promotes Both M1/M2 Polarization and MMP Production in Cigarette Smoke-Exposed Macrophages." dans: Frontiers in immunology, Vol. 11, pp. 1902, (2020) (PubMed).

Bai, Wang, Wang, Li, Zhao, Wu, Yang, Deng, Zhang: "The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 5, pp. 1882-1895, (2018) (PubMed).

Sollazzo, Forte, Polverelli, Romano, Perricone, Rossi, Ottaviani, Luatti, Martinelli, Vianelli, Cavo, Palandri, Catani: "Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study." dans: Oncotarget, Vol. 7, Issue 28, pp. 43974-43988, (2018) (PubMed).

Forte, Salvestrini, Corradi, Rossi, Catani, Lemoli, Cavo, Curti: "The tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signaling." dans: Oncotarget, Vol. 8, Issue 2, pp. 2261-2274, (2018) (PubMed).

Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." dans: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).

Liang, Xiao, Long, Liu, Li, Liu, Yang: "Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy." dans: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1781-1791, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à TIMP1

TIMP metallopeptidase inhibitor 1 (TIMP1), TIMP metallopeptidase inhibitor 1 (Timp1), tissue inhibitor of metalloproteinase 1 (Timp1), CLGI, Clgi, DKFZp468A0912, EPA, EPO, HCI, TIMP, Timp, TIMP-1, TIMP1

Protein level used designations for TIMP1

  • tissue inhibitor of matrix metalloproteinase-1
  • TIMP metallopeptidase inhibitor 1
  • Metalloproteinase inhibitor 1
  • TIMP-1
  • collagenase inhibitor
  • erythroid potentiating activity
  • erythroid-potentiating activity
  • fibroblast collagenase inhibitor
  • metalloproteinase inhibitor 1
  • tissue inhibitor of metalloproteinases 1
  • EG-1
  • embryogenin-1
  • tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
  • tissue inhibitor of metallopeptidase 1
  • tissue inhibitor of metalloproteinase 1
  • metalloproteinase tissue inhibitor
  • metalloproteinase tissue inhibitor 1
  • EPA
  • TPA-S1
  • TPA-induced protein
  • collagenase inhibitor 16C8 fibroblast
  • tissue inhibitor of metalloproteinase-1
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