TNR1A Protein (AA 31-210) (GST tag)
TNR1A
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Antigène
- TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 31-210
- Origine
- Humain
- Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TNR1A protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
- Purification
- SDS-PAGE
- Pureté
- > 90 %
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Antigène
- TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
- Autre désignation
- TNR1A
- Sujet
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
- Poids moléculaire
- 47.6 kDa
- UniProt
- P19438
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