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TRKA Produits

(Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].

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Catégories TRKA en vedette

TRKA Anticorps

High quality antibodies with extensive validation data.

TRKA Kits ELISA

Reliable ELISA kits for a wide range of species.

TRKA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRKA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (11)
N° du produit ABIN6256787
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN726110
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7155192
Quantité 100 μg
Fiche technique Fiche technique

TRKA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968899
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968898
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN1720665
Quantité 96 tests
Fiche technique Fiche technique

TRKA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5570030
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7321090
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7320045
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TRKA

Desiderio, Vermeiren, Van Campenhout, Kricha, Malki, Richts, Fletcher, Vanwelden, Schmidt, Henningfeld, Pieler, Woods, Nagy, Verfaillie, Bellefroid: "Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA." dans: Cell reports, Vol. 26, Issue 13, pp. 3522-3536.e5, (2019) (PubMed).

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." dans: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).

Alshawaf, Viventi, Qiu, DAbaco, Nayagam, Erlichster, Chana, Everall, Ivanusic, Skafidas, Dottori: "Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells." dans: Scientific reports, Vol. 8, Issue 1, pp. 603, (2018) (PubMed).

Herbrich, Kannan, Nolo, Hornbaker, Chandra, Zweidler-McKay: "Characterization of TRKA signaling in acute myeloid leukemia." dans: Oncotarget, Vol. 9, Issue 53, pp. 30092-30105, (2018) (PubMed).

Choi, Won, Lee, Kim, Kim, Park, Jo, Song, Kwon, Park: "Cytoplasmic TrkA Expression as a Screen for Detecting NTRK1 Fusions in Colorectal Cancer." dans: Translational oncology, Vol. 11, Issue 3, pp. 764-770, (2018) (PubMed).

Ullrich, Weber, Post, Popp, Grein, Zechner, Guerrero González, Kreis, Schmitt, Üçeyler, Lesch, Schuh: "OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency." dans: Molecular psychiatry, (2017) (PubMed).

Chakraborty, Castranova, Perez, Piedimonte: "Nanoparticles increase human bronchial epithelial cell susceptibility to respiratory syncytial virus infection via nerve growth factor-induced autophagy." dans: Physiological reports, Vol. 5, Issue 13, (2017) (PubMed).

Boucrot, Ferreira, Almeida-Souza, Debard, Vallis, Howard, Bertot, Sauvonnet, McMahon: "Endophilin marks and controls a clathrin-independent endocytic pathway." dans: Nature, Vol. 517, Issue 7535, pp. 460-5, (2015) (PubMed).

Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." dans: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).

Paczkowska, Kaczy?ska, Pius-Sadowska, Rogi?ska, Kawa, Ustianowski, Safranow, Celewicz, Machali?ski: "Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders." dans: PLoS ONE, Vol. 8, Issue 12, pp. e83833, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à TRKA

neurotrophic receptor tyrosine kinase 1 (NTRK1), ret proto-oncogene (RET), neurotrophic receptor tyrosine kinase 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), C80751, CDHF12, CDHR16, CTRKA, HSCR1, MEN2A, MEN2B, MTC, MTC1, p140-TrkA, PTC, RET-ELE1, RET51, Tkr, TRK, Trk, trk, Trk-A, TRK1, TRKA, TrkA, trka, trkA

Protein level used designations for TRKA

  • Oncogene TRK
  • TRK1-transforming tyrosine kinase protein
  • gp140trk
  • high affinity nerve growth factor receptor
  • tropomyosin-related kinase A
  • tyrosine kinase receptor A
  • RET transforming sequence
  • cadherin family member 12
  • cadherin-related family member 16
  • hydroxyaryl-protein kinase
  • proto-oncogene c-Ret
  • proto-oncogene tyrosine-protein kinase receptor Ret
  • receptor tyrosine kinase
  • ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
  • TrkA neurotrophin receptor
  • p140-TrkA
  • slow nerve growth factor receptor
  • trk
  • trk-A
  • trkA proto-oncogene receptor
  • neurotrophic tyrosine kinase receptor type 1
  • tropomyosin receptor kinase
  • neurotrophic tyrosine kinase, receptor, type 1
  • high affinity nerve growth factor receptor-like
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