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TTR Produits

(Transthyretin (TTR))
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein\; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported\; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009].

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Catégories TTR en vedette

TTR Anticorps

High quality antibodies with extensive validation data.

TTR Kits ELISA

Reliable ELISA kits for a wide range of species.

TTR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TTR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (5)
N° du produit ABIN3021474
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (7)
N° du produit ABIN5542369
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7429271
Quantité 100 μL
Fiche technique Fiche technique

TTR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (6)
N° du produit ABIN6574196
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6960157
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN7041488
Quantité 96 tests
Fiche technique Fiche technique

TTR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275811
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275810
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125488
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TTR

Jensen, Schefe, Jacobsen, Mølck, Almholt, Sjögren, Dalsgaard, Kirk, Benie, Petersen, Kyhn, Overgaard, Bjørnsdottir, Stannard, Offenberg, Egecioglu et al.: "Normal Neurodevelopment and Fertility in Juvenile Male Rats Exposed to Polyethylene Glycol Following Dosing With PEGylated rFIX (Nonacog Beta Pegol, N9-GP): Evidence from a 10-Week Repeat-Dose ..." dans: International journal of toxicology, Vol. 41, Issue 6, pp. 455-475, (2022) (PubMed).

Tesch, Abdirama, Grießbach, Brand, Goerlich, Humrich, Bacher, Hiepe, Riemekasten, Enghard: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." dans: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).

Zarif, Paquet, Lebrigand, Arguel, Heurteaux, Glaichenhaus, Chabry, Guyon, Petit-Paitel: "CD4+ T Cells Affect the Thyroid Hormone Transport at the Choroid Plexus in Mice Raised in Enriched Environment." dans: Neuroimmunomodulation, Vol. 26, Issue 2, pp. 59-66, (2020) (PubMed).

Kumar, Paramasivam, Devasia, K, A, Nayak, Joshi, Moka: "Primary Cardiac Involvement in the Rare Transthyretin Ile73Val Mutation: A Case Series." dans: Circulation. Genomic and precision medicine, Vol. 13, Issue 3, pp. e002792, (2020) (PubMed).

Cheng, Xu, Yi, Sun, Yang, Yu, Yang, Jin, Tu, Zhang: "iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management." dans: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 1, pp. 216-232, (2019) (PubMed).

Songstad, Worthington, Chirco, Giacalone, Whitmore, Anfinson, Ochoa, Cranston, Riker, Neiman, Stone, Mullins, Tucker: "Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium." dans: Stem cells translational medicine, Vol. 6, Issue 6, pp. 1533-1546, (2019) (PubMed).

Wegmann, Neri, Schuierer, Bilican, Hartkopf, Nigsch, Mapa, Waldt, Cuttat, Salick, Raymond, Kaykas, Roma, Keller: "CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data." dans: Genome biology, Vol. 20, Issue 1, pp. 142, (2019) (PubMed).

Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." dans: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).

Wu, Cui, Yang, Fan, Liu, Wang, An: "Zika Virus Infection in Hypothalamus Causes Hormone Deficiencies and Leads to Irreversible Growth Delay and Memory Impairment in Mice." dans: Cell reports, Vol. 25, Issue 6, pp. 1537-1547.e4, (2018) (PubMed).

Zhang, Chen, Song, Li, Sun, Xiao, Xing: "Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway." dans: Experimental cell research, Vol. 347, Issue 2, pp. 350-9, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à TTR

transthyretin (prealbumin, amyloidosis type I) (ttr), transthyretin (TTR), transthyretin (vpb38), transthyretin (MRAD2831_RS38185), Transthyretin (Caci_4246), transthyretin (prealbumin, amyloidosis type 1) (ttr), transthyretin-like (LOC100226992), transthyretin (Ttr), transthyretin L homeolog (ttr.L), AA408768, AI787086, CTS, CTS1, D17860, HsT2651, LOC100226992, Lr1, PALB, prealbumin, Prealbumin, TBPA, Tbpa, TTR, xTTR, zgc:103583

Protein level used designations for TTR

  • transthyretin
  • transthyretin (prealbumin, amyloidosis type I)
  • Transthyretin
  • transthyretin (prealbumin, amyloidosis type 1)
  • ATTR
  • carpal tunnel syndrome 1
  • prealbumin, amyloidosis type I
  • thyroxine-binding prealbumin
  • TBPA
  • prealbumin
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