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USP18 Protéines

(Ubiquitin Specific Peptidase 18 (USP18))
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011].

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custom-made USP18 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N° du produit ABIN7544988
 
USP18 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
N° du produit ABIN7125590
 
USP18 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
N° du produit ABIN1324763
 
USP18 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
N° du produit ABIN1324762
 
custom-made USP18 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
N° du produit ABIN3075216
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
  • Réactivité
    • Human
  • Images disponible
  • Carrier free only
  • Hote
    • Wheat germ
    • Cell-free protein synthesis (CFPS)
    • Escherichia coli (E. coli)
    • HEK-293 Cells
  • Epitope
    • AA 1-372
    • AA 18-268
    • AA 273-372
  • Conjugué
    • GST tag
    • His tag
    • His-IF2DI Tag
    • Strep Tag
  • Type Proteine
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online

Pseudonymes pour USP18 Protéines

ubiquitin specific peptidase 18 (USP18) Protéines
ubiquitin specific peptidase 18 (Usp18) Protéines
1110058H21Rik Protéines
AW047653 Protéines
bubp43 Protéines
ISG43 Protéines
UBP Protéines
Ubp15 Protéines
UBP43 Protéines
USP18 Protéines
USP41 Protéines
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