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USP2 Protéines

(Ubiquitin Specific Peptidase 2 (USP2))

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].

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USP2 Protein (AA 1-605) (His tag)

custom-made USP2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant USP2 Protein, UniprotID O75604

3 images

N° du produit ABIN7555895

Détails

USP2 Protein (AA 1-206) (His tag)

USP2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

N° du produit ABIN7420525

Détails

USP2 Protein (AA 1-219) (His tag)

USP2 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % SDS, WB, Imm, PC

N° du produit ABIN7420528

Détails

USP2 Protein (AA 1-605) (Strep Tag)

custom-made USP2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3096154