VAMP1/VAMP2 anticorps (full length)
Aperçu rapide pour VAMP1/VAMP2 anticorps (full length) (ABIN306588)
Antigène
Reactivité
Hôte
Clonalité
Application
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Épitope
- full length
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Fonction
- Sheep anti Human Vesicle Associated Membrane Protein (VAMP 1/2)
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Réactivité croisée
- Humain
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Attributs du produit
- Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.
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Purification
- Ammonium Sulfate Precipitation
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Immunogène
- Full length VAMP1/2 protein
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Isotype
- IgG
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Indications d'application
- Applications: Western Blotting, Immunoprecipitation
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
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Autre désignation
- Vesicle Associated Membrane Protein (VAMP 1/2)
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Sujet
- Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2
Antigène
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