Cet anticorps anti-VAMP1/VAMP2 Polyclonal Mouton (ABIN306588) détecte spécifiquement VAMP1/VAMP2 dans IP et WB.
L’anticorps est réactif avec des échantillons de Humain et Rat.
Aperçu rapide pour VAMP1/VAMP2 anticorps (full length) (ABIN306588)
Antigène
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Reactivité
Humain, Rat
Hôte
Mouton
Clonalité
Polyclonal
Application
Immunoprecipitation (IP), Western Blotting (WB)
Épitope
full length
Fonction
Sheep anti Human Vesicle Associated Membrane Protein (VAMP 1/2)
Réactivité croisée
Humain
Attributs du produit
Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.
Purification
Ammonium Sulfate Precipitation
Immunogène
Full length VAMP1/2 protein
Isotype
IgG
Indications d'application
Applications: Western Blotting, Immunoprecipitation
Restrictions
For Research Use only
Format
Liquid
Buffer
phosphate buffered saline with 0.08 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Antigène
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Autre désignation
Vesicle Associated Membrane Protein (VAMP 1/2)
Sujet
Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2