WASF1 Produits
(WAS Protein Family, Member 1 (WASF1))
Catégories
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories WASF1 en vedette
WASF1 Anticorps
High quality antibodies with extensive validation data.
WASF1 Kits ELISA
Reliable ELISA kits for a wide range of species.
WASF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
WASF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
N° du produit
ABIN7175830
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6266012
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7138927
Quantité
100 μL
Fiche technique
Fiche technique
WASF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380279
Quantité
2 x 96 tests
Fiche technique
Fiche technique
WASF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325156
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3075433
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Yeast
Validations
N° du produit
ABIN1630881
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits WASF1
: "Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion." dans: The EMBO journal, Vol. 33, Issue 23, pp. 2745-64, (2014) (PubMed).: "The WAVE regulatory complex links diverse receptors to the actin cytoskeleton." dans: Cell, Vol. 156, Issue 1-2, pp. 195-207, (2014) (PubMed).
: "Local F-actin network links synapse formation and axon branching." dans: Cell, Vol. 156, Issue 1-2, pp. 208-20, (2014) (PubMed).
: "SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties." dans: Nature, Vol. 503, Issue 7474, pp. 72-7, (2013) (PubMed).
: "Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel." dans: Hypertension (Dallas, Tex. : 1979), Vol. 57, Issue 5, pp. 996-1002, (2011) (PubMed).
: "Rac1 regulates neuronal polarization through the WAVE complex." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 20, pp. 6930-43, (2010) (PubMed).
: "Major signaling pathways in migrating neuroblasts." dans: Frontiers in molecular neuroscience, Vol. 2, pp. 7, (2009) (PubMed).
: "WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2." dans: Nature cell biology, Vol. 10, Issue 7, pp. 849-57, (2008) (PubMed).
: "Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 7, pp. 1519-28, (2007) (PubMed).
: "Src-dependent phosphorylation of Scar1 promotes its association with the Arp2/3 complex." dans: Cell motility and the cytoskeleton, Vol. 63, Issue 1, pp. 6-13, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à WASF1
WAS protein family member 1 S homeolog (wasf1.S), SCAR family protein (AT2G34150), WAS protein family member 1 (wasf1), WAS protein family member 1 (WASF1), WAS protein family, member 1 (Wasf1), AI195380, AI838537, ATRANGAP2, ATSCAR1, Scar, scar1, SCAR1, T14G11.27, T14G11_27, wave, WAVE, WAVE-1, wave1, WAVE1, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1Protein level used designations for WASF1
- WASP family protein member 1
- homology of dictyostelium scar 1
- protein WAVE-1
- verprolin homology domain-containing protein 1
- wiskott-Aldrich syndrome protein family member 1
- WASP family 1
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